12/18/2023 0 Comments Liquid war algorithmDietary iodine intakes in the caption of Figure 1 refers to intake of stable KI, not I-131.įigure 1.The higher the number on the y-axis the more dose is averted.Note that the y-axis is in arbitrary units of averted dose, not a specific dose.It is a conceptual graphic that should NOT be used clinically.Figure 1 below shows the effectiveness of thyroid blocking achieved by administering stable iodine at different times before (only at 1.2 hours) or various times after a 4-hours intake (inhalation) of I-131.Since the protective effect of a single dose of KI lasts approximately 24 hours, repeat KI administration may be indicated for some members of the public where contamination is continuing or ongoing.KI is even less effective at preventing radioiodine uptake by the thyroid if taken more than 12 hours of a time-limited contamination episode.If KI is taken more than 4 hours after inhalation of I-131, much less thyroid uptake of I-131 is blocked.Taking KI within 1 to 2 hours after inhalation of I-131 can block more than 90% of the radioactive iodine uptake by the thyroid.KI is highly effective if taken several hours before inhaled contamination with radioactive iodine.KI does NOT prevent or treat problems due to internal contamination from any other isotope. KI is effective as a radiation medical countermeasure only for internal contamination with radioactive iodine.KI does not provide protection for any other organs. KI protects only the thyroid from radioactive iodine uptake.Potassium iodide (KI) blocks uptake of radioactive iodine by the thyroid gland.Potassium Iodide (KI): Instructions to Make Potassium Iodide Solution for Use During a Nuclear Emergency (Liquid Form) and KI Palatability and Stability References (HHS/FDA, March, 2018).Frequently Asked Questions on Potassium Iodide (KI) (HHS/FDA, October, 2016).Potassium Iodide (KI) (HHS/CDC, March, 2011).Radiation and Potassium Iodide (KI) (HHS/CDC, March, 2011).The easiest way to reduce or eliminate internal contamination from I-131 following a release is to find an alternate source of food items produced outside the contamination zone.Time the products were consumed relative to the time of the release (which takes into account half-life and radioactive decay rate of I-131).The amount and type of milk and milk products consumed.After I-131 ingestion, the most critical dietary information needed is.The concentration of I-131 in milk from goats and sheep is 10 times higher than the concentration in cow's milk. ( Illustration) Deposition of I-131 on pasture grasses, followed by I-131 ingestion by cows or goats and then human ingestion of contaminated milk and fresh dairy products may occur. Historically, milk consumption has been a more significant route of internal contamination than inhalation, both in terms of numbers of individuals affected and internal dose.Doses to humans from inhalation or from ingestion of plants, animals, or water, however, are usually small in comparison to that from milk intake (see below). Ingestion: Where I-131 is not inhaled, ingestion may represent a more significant route of internal contamination.Inhalation: represents one route of internal contamination of public health significance.External contamination may occur when a person is caught in the plume or passes through an area left contaminated by fallout from the plume.Contamination with I-131 begins immediately for persons within the plume in the immediate vicinity of a nuclear release (e.g.Meteorological conditions at and after the time of the release.Distance between a given individual and the place of release.After an I-131 release, the amount of the radioisotope available to contaminate the public depends on.Untoward releases of I-131 requiring medical management are rare.Radioactive iodine is difficult to obtain in quantity and is not considered a likely isotope for use in a Radiological Dispersal Device (RDD).Most I-131 distributes over large distances, typically with only 10% making its way to the earth's surface before undergoing spontaneous radioactive decay to stable xenon-131. Nuclear bomb detonation produces a small amount of local I-131 fallout.I-131 releases have occurred most frequently after incidents involving nuclear reactors (e.g., Chernobyl, Japan).Time Line of Potassium Iodide Distribution Policies in the US.KI information sheet for the general public (HHS/CDC). How to Follow Patients Exposed to I-131.You are here: Home > Managing Internal Contamination Countermeasures - Use of Myeloid Cytokines.Template for Hospital Orders (Adults/Children).
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